Brain Biopsy in a Patient Suffering from Primary CNS Lymphoma Treated with Steroids

Mokhtari K et al.

Brain Biopsy in a Patient Suffering from Primary CNS Lymphoma Treated with Steroids

European Association of NeuroOncology Magazine 2012; 2 (2): 95-96

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Maximize View	Gadolinium Injection Figure 1a-b: MRI axial T1-weighted sequences with gadolinium injection (a) before steroid administration and (b) after one week of steroid administration major partial response. Keywords: brain, gadolinium injection, MRI


Maximize View	Brain biopsy Figure 2a-d: Brain biopsy. (a) Large macrophages with a perivascular tropism. (b) High magnification: prominent astrocytic and microglial response without atypical cells. (c) Expression of CD68 by macrophagic cells. (d) Accumulation of large CD20-positive cells within the perivascular space, suggesting a primary, diffuse large B-cell lymphoma with post-corticosteroid macrophagic detersion. Keywords: brain biopsy