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EUROPA-Studie (Perindopril) (60 Abbildungen)
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Zum ersten Bild Abb. 20: Perindopril - Antiatheriosklerotischer Effekt Abb. 21: Perindopril - Antiischämische Wirksamkeit Abb. 22: Perindopril - Verträglichkeit Aktuelles Bild - Abb. 23: Perindopril - Verträglichkeit Abb. 24: EUROPA-Studie - Studienziel Abb. 25: EUROPA-Studie - Endpunkte Abb. 26: EUROPA-Studie - Studiendesign Zum letzten Bild
Abbildung 23: Perindopril - Verträglichkeit
Coversyl once daily maintains cerebral blood flow in patients with acute ischemic stroke. There is an obvious theoretical concern that Bp lowering agent may also cause an adverse reduction in cerebral blood flow. In patients with already compromised cerebral circulation (ie, those who have had a stroke) this would clearly be highly undesirable. However it appears Coversyl provides BP controls without any adverse effects on cerebral blood flow. In a study of 28 patients with acute stroke and hypertension, between 48 hours and 7 days after a stroke, patients were randomized to either Coversyl once daily or placebo. The comparison with the placebo curve is particularly important in the context of a stroke because of the spontaneous wide variations of blood pressure in the acute phase ( first weeks). Cerebral blood flow was calculated from internal carotid artery Doppler ultrasound measurements. These measurements were undertaken 3 times: before intake of Coversyl, during the first 24 hours, and then repeated after 2 weeks. The results show that Coversyl reduces BP while maintaining cerebral blood flow.
 
Perindopril - Verträglichkeit
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Abbildung 23: Perindopril - Verträglichkeit
Coversyl once daily maintains cerebral blood flow in patients with acute ischemic stroke. There is an obvious theoretical concern that Bp lowering agent may also cause an adverse reduction in cerebral blood flow. In patients with already compromised cerebral circulation (ie, those who have had a stroke) this would clearly be highly undesirable. However it appears Coversyl provides BP controls without any adverse effects on cerebral blood flow. In a study of 28 patients with acute stroke and hypertension, between 48 hours and 7 days after a stroke, patients were randomized to either Coversyl once daily or placebo. The comparison with the placebo curve is particularly important in the context of a stroke because of the spontaneous wide variations of blood pressure in the acute phase ( first weeks). Cerebral blood flow was calculated from internal carotid artery Doppler ultrasound measurements. These measurements were undertaken 3 times: before intake of Coversyl, during the first 24 hours, and then repeated after 2 weeks. The results show that Coversyl reduces BP while maintaining cerebral blood flow.
 
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