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Rupp H, Jäger B The renin-angiotensin system and the sympathetic nervous system in hypertension and congestive heart failure: implications for therapeutic interventions Journal of Clinical and Basic Cardiology 2001; 4 (1): 47-51 PDF Summary Overview
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Figure/Graphic 2: Sympathisches Nervensystem - Blutgefäß Sympathetic neuroeffector junction. Norepinephrine (NE) is released from the sympathetic nerve at the sympathetic neuroeffector junction, stimulating postsynaptic alpha1-adrenoreceptors (a1) leading to vasoconstriction. Angiotensin AT1 receptors are present presynaptically at this junction as well as postsynaptically on blood vessels. Stimulation of the presynaptic receptors enhances SNS-induced norepinephrine release. Adapted from Ohlstein [21, 22]. |
Figure/Graphic 2: Sympathisches Nervensystem - Blutgefäß
Sympathetic neuroeffector junction. Norepinephrine (NE) is released from the sympathetic nerve at the sympathetic neuroeffector junction, stimulating postsynaptic alpha1-adrenoreceptors (a1) leading to vasoconstriction. Angiotensin AT1 receptors are present presynaptically at this junction as well as postsynaptically on blood vessels. Stimulation of the presynaptic receptors enhances SNS-induced norepinephrine release. Adapted from Ohlstein [21, 22]. |