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Gasser R, Byon YK, Fleckenstein A, Fleckenstein-Grün G, Frey G Some observations on Ca-overload in rat ventricular tissue Journal of Clinical and Basic Cardiology 1999; 2 (2): 255-258 PDF Summary Overview
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Figure/Graphic 2: Mykard - Kalzium Myocardial (Ca++)i in rat papillary muscle at rest. In those rats which received high dose vit. D3, (Ca++)i was increased over 160 times. This rather dramatic rise in (Ca++)i could be largely prevented by s.c. administration of diltiazem and verapamil. |
Figure/Graphic 2: Mykard - Kalzium
Myocardial (Ca++)i in rat papillary muscle at rest. In those rats which received high dose vit. D3, (Ca++)i was increased over 160 times. This rather dramatic rise in (Ca++)i could be largely prevented by s.c. administration of diltiazem and verapamil. |