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Dia-Präsentation von Merck Gesellschaft mbH.
Micardis(R) - MicardisPlus(R) - Hypertonie (38 Abbildungen)
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Zum ersten Bild Abb. 18: Endothel - Kardiovaskuläres Risiko Abb. 19: Linksventrikuläre Hypertrophie - Kardiovaskuläres Risiko Abb. 20: Albuminurie - Kardiovaskuläres Risiko Aktuelles Bild - Abb. 21: Kardiovaskuläres Risiko - Blutdrucksenkung Abb. 22: Blutdrucksenkung - Zielorganschäden Abb. 23: Blutdrucksenkung - Vorteile Abb. 24: Antihypertensive Behandlungsziele Zum letzten Bild
Abbildung 21: Kardiovaskuläres Risiko - Blutdrucksenkung
A meta-analysis of 61 prospective, observational studies has shown that a 10 mmHg lower S BP is associated over the long term with a 40% lower risk of stroke death and a 30% lower risk of death from ischaemic heart disease (IHD) or other vascular causes.1 Even a small, 2 mmHg fall in mean S BP was associated with large reductions in premature deaths and disabling strokes.1 There was no evidence of a J-curve (i.e. a threshold of reduction beyond which risk begins to increase).1 The reduction in risk associated with a given reduction in mean blood pressure is approximately constant down to at least an SBP of 115 mmHg and a DBP of 75 mmHg – well beyond what is normally achieved.1 The reduction in risk holds for all age groups assessed from 40 up to 89 years old.1 1. Lewington S, et al. Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies. Lancet 2002; 360: 1903–1913.
 
Kardiovaskuläres Risiko - Blutdrucksenkung
Vorheriges Bild Nächstes Bild   


Abbildung 21: Kardiovaskuläres Risiko - Blutdrucksenkung
A meta-analysis of 61 prospective, observational studies has shown that a 10 mmHg lower S BP is associated over the long term with a 40% lower risk of stroke death and a 30% lower risk of death from ischaemic heart disease (IHD) or other vascular causes.1 Even a small, 2 mmHg fall in mean S BP was associated with large reductions in premature deaths and disabling strokes.1 There was no evidence of a J-curve (i.e. a threshold of reduction beyond which risk begins to increase).1 The reduction in risk associated with a given reduction in mean blood pressure is approximately constant down to at least an SBP of 115 mmHg and a DBP of 75 mmHg – well beyond what is normally achieved.1 The reduction in risk holds for all age groups assessed from 40 up to 89 years old.1 1. Lewington S, et al. Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies. Lancet 2002; 360: 1903–1913.
 
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