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Micardis(R) - Micardis Plus(R) - Klinische Wirksamkeit (39 Abbildungen)
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Zum ersten Bild Abb. 26: Telmisartan - Eigenschaften Abb. 27: Morgendliche Blutdrucksenkung Abb. 28: Klinische Wirksamkeit - MicardisPlus Aktuelles Bild - Abb. 29: Telmisartan - HCTZ Abb. 30: Telmisartan - HCTZ Abb. 31: Telmisartan - HCTZ Abb. 32: Telmisartan - Losartan - HCTZ Zum letzten Bild
Abbildung 29: Telmisartan - HCTZ
Reported here are selected arms from an 8-week, 4 x 5 factorial, multicentre, double-blind, placebo-controlled, dose-finding study conducted in 818 patients with mild-to-moderate hypertension.1 Patients were randomized to telmisartan 20 mg, 40 mg, 80 mg or 160 mg alone or in combination with HCTZ 6.25 mg, 12.5 mg, or 25 mg, giving a total of 20 treatment groups. SBP was significantly lowered with telmisartan 40 mg/HCTZ 12.5 mg compared with telmisartan 40 mg or HCTZ 12.5 mg monotherapies (P<0.01), and was significantly lowered with telmisartan 80 mg/HCTZ 12.5 mg compared with telmisartan 40/80 mg or HCTZ 12.5 mg monotherapies (P<0.01). 1. McGill JB, Reilly PA. Telmisartan plus hydrochlorothiazide versus telmisartan or hydrochlorothiazide monotherapy in patients with mild to moderate hypertension: a multicenter, randomized, double-blind, placebo-controlled, parallel-group trial. Clin Ther 2001;23:833–850.
 
Telmisartan - HCTZ
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Abbildung 29: Telmisartan - HCTZ
Reported here are selected arms from an 8-week, 4 x 5 factorial, multicentre, double-blind, placebo-controlled, dose-finding study conducted in 818 patients with mild-to-moderate hypertension.1 Patients were randomized to telmisartan 20 mg, 40 mg, 80 mg or 160 mg alone or in combination with HCTZ 6.25 mg, 12.5 mg, or 25 mg, giving a total of 20 treatment groups. SBP was significantly lowered with telmisartan 40 mg/HCTZ 12.5 mg compared with telmisartan 40 mg or HCTZ 12.5 mg monotherapies (P<0.01), and was significantly lowered with telmisartan 80 mg/HCTZ 12.5 mg compared with telmisartan 40/80 mg or HCTZ 12.5 mg monotherapies (P<0.01). 1. McGill JB, Reilly PA. Telmisartan plus hydrochlorothiazide versus telmisartan or hydrochlorothiazide monotherapy in patients with mild to moderate hypertension: a multicenter, randomized, double-blind, placebo-controlled, parallel-group trial. Clin Ther 2001;23:833–850.
 
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