Influence on Plasma-Insulin and Blood-Glucose by Treatment with Bisoprolol in Hypertensive, Non-Diabetic Patients
Journal of Clinical and Basic Cardiology 2001; 4 (3): 229-230
Keywords: Bisoprolol, Blutglukose, Hypertonie, Kardiologie, Plasmainsulin, Bisoprolol, blood glucose, cardiology, hypertension, plasma-insulin
Beta-blockers have been shown to worsen insulin resistance and deteriorate lipoprotein metabolism in hypertensive patients. However, beta-1 selective beta-blockers seem to offer some advantage over non-selective ones and the degree of beta-1 selectivity is of importance. Thirty patients with primary hypertension were treated with the highly beta-1 selective beta-blocker bisoprolol for three months. There was a highly significant reduction of the blood pressure but no changes in fasting plasma-glucose or plasma-insulin levels were observed.