Thrombophilia and cancer in the pathogenesis of arterial thrombosis

Journal of Clinical and Basic Cardiology 2000; 3 (2): 89-90

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Keywords: arterielle Thrombose,  Homocystein,  Krebs,  Thrombophilie,  arterial thrombosis,  cancer,  homocysteine,  thrombophilia

Hereditary and acquired abnormalities in blood coagulation may predispose for arterial thrombosis. The rapidly growing list of heritable thrombophilic states involves mutations in coagulation factors and deficiencies of inhibitors of the coagulation system. Hyperhomocysteinaemia is an emerging risk factor for arterial thrombosis resulting from hereditary causes like thermolabile meythlene tetra hydrofolate reductase and from nutritional abnormalities, notably folic acid deficiency. Cancer is a well known cause of arterial thrombosis by several pathogenic mechanisms which may activate blood coagulation. J Clin Basic Cardiol 2000; 3: 89?90