Abbildung 7: Verträglichkeitsprofil
This study, A comparison of Telmisartan plus HCTZ with amlodipine plus HCTZ in Older patients with predominantly Systolic hypertension (ATHOS), compared telmisartan 40–80 mg + HCTZ 12.5 mg and amlodipine 5–10 mg + HCTZ 12.5 mg.1 There were more adverse events in the amlodipine group than in the telmisartan group. The most frequently reported adverse event was peripheral oedema, reported in 6 (1.2%) patients taking telmisartan + HCTZ, compared with 122 (24.3%) patients taking amlodipine + HCTZ. This led to a higher overall discontinuation rate from adverse events in the amlodipine group compared with the telmisartan group. Data on file. Boehringer Ingelheim, GmbH.