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Figures and Graphics
Gasser R et al.  
Immunological Implications in Experimental Myocardial Ischaemia: MPO (Myeloperoxidase) Expression Is Differentially Regulated by Beta-Blockers, While CD80 Expression Remains Unaffected

Journal of Clinical and Basic Cardiology 2011; 14 (1-4): 16-22

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Figure
 
MPO Experiments
Figure 1: It shows the results from real-time PCR measurements of all MPO experiments (o2ko: well-oxygenated, no ischaemia, no drug; n2ko: experimental ischaemia, no drug; o2at: well-oxygenated, no ischaemia, atenolol present; n2at: experimental ischaemia, atenolol present; o2neb: well-oxygenated, nebivolol present; n2neb: experimental ischaemia, nebivolol present). Using PCR for validation, we find that during experimental ischaemia, there is an up-regulation of MPO expression. There is a differential regulation between different beta-blockers during myocardial ischaemia, which warrants further investigation.


Keywords: flowchartMPO
 
 
Interleukin Pathway
Figure 2: Interleukin pathway up-regulated by nebivolol, not by atenolol, during experimental ischaemia.


Keywords: flowchartinterleukin
 
 
CD80 Experiments
Figure 3: It shows the results from real-time PCR measurements of all CD80 experiments (o2ko: well-oxygenated, no ischaemia, no drug; n2ko: experimental ischaemia, no drug; o2at: well-oxygenated, no ischaemia, atenolol present; n2at: experimental ischaemia, atenolol present; o2neb: well-oxygenated, nebivolol present; n2neb: experimental ischaemia, nebivolol present). It can be seen that during experimental ischaemia, there is an up-regulation of CD80 expression. There is also a regulation with and without the influence of beta-blockers during myocardial ischaemia.


Keywords: CD80flowchart
 
 
 
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