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Borchard U
The Role of the Sympathetic Nervous System in Cardiovascular Disease
Journal of Clinical and Basic Cardiology 2001; 4 (3): 175-177

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Fig. 1: Framingham - Herzfrequenz Fig. 2: SNS-Überaktivität - kardiovaskuläre Erkrankung Fig. 3: SNS-Überaktivität - Hypertrophie Fig. 4: SNS-Überaktivität - Metabolismus Fig. 5: Moxonidin - Imidazolinrezeptor This Image - Fig. 6: Imidazolinantagonisten
Figure/Graphic 6: Imidazolinantagonisten
There is a strong correlation between the affinity of different I1-agonists at the I1-receptor in the ventrolateral medulla (VLM) and the oral dose needed to lower blood pressure in hypertensive patients. There is no such correlation for Ki at a2-receptors (modified according to [15])
 
Imidazolinantagonisten
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Figure/Graphic 6: Imidazolinantagonisten
There is a strong correlation between the affinity of different I1-agonists at the I1-receptor in the ventrolateral medulla (VLM) and the oral dose needed to lower blood pressure in hypertensive patients. There is no such correlation for Ki at a2-receptors (modified according to [15])
 
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