Gasser R, Horn S, Köppel H Discrimination by valinomycin K-selective surface microelectrodes of a sulphonylurea-sensitive and a distinct sulphonylurea-, barium-, TEA- and cinnamate-insensitive component of K-efflux from isolated pig coronary arteries during simulated ischaemia Journal of Clinical and Basic Cardiology 1998; 1 (1): 43-51 PDF Summary Overview
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Figure/Graphic 8A-B: K-Efflux in Koronararterien A. Lack of effect of alpha-cyano-4-hydroxycinnamate (cinnamate, a lactate transport inhibitor) on ischaemia induced K+ efflux in an isolated pig coronary artery strip. Preparation has been incubated with 4 mM cinnamate for 15 minutes before beginning of trace in right hand panel. Left and right hand panel from the same preparation. Gap represents 20 min. B. In Cl-- free solution (Cl- replaced by glucuronate one hour before testing the effect of simulated ischaemia) rate and extent of K+ accumulation are the same as in the presence of Cl-. Gap represents 60 min. Left and right hand panel from the same preparation (like in A). |
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Figure/Graphic 8A-B: K-Efflux in Koronararterien
A. Lack of effect of alpha-cyano-4-hydroxycinnamate (cinnamate, a lactate transport inhibitor) on ischaemia induced K+ efflux in an isolated pig coronary artery strip. Preparation has been incubated with 4 mM cinnamate for 15 minutes before beginning of trace in right hand panel. Left and right hand panel from the same preparation. Gap represents 20 min. B. In Cl-- free solution (Cl- replaced by glucuronate one hour before testing the effect of simulated ischaemia) rate and extent of K+ accumulation are the same as in the presence of Cl-. Gap represents 60 min. Left and right hand panel from the same preparation (like in A). |