Pituitary Corticotroph Microadenomas Versus Macroadenomas Causing Cushing’s Disease

Journal für Klinische Endokrinologie und Stoffwechsel - Austrian Journal of Clinical Endocrinology and Metabolism 2014; 7 (3): 96-101

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Prevalence of pituitary corticotroph macroadenomas was higher than presumed. Although patients with corticotroph macroadenomas and microadenomas share similar biochemical evidence of hypercortisolism, remission and recurrence rates, their clinical manifestations are significantly different. The more subtle clinical presentation of patients with corticotroph macroadenomas may have been due to a shorter manifestation time because of more progressive tumour growth.