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Rupp H, Jäger B  
The renin-angiotensin system and the sympathetic nervous system in hypertension and congestive heart failure: implications for therapeutic interventions

Journal of Clinical and Basic Cardiology 2001; 4 (1): 47-51

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Figure 1: The relationship between the renin-angiotensin system and the sympathetic nervous system (SNS)

Keywords: RASRASrenin-angiotensin systemRenin-Angiotensin-SystemSchemaSNSSNSsympathetic nervous systemSympathikussympathisches Nervensystem
Sympathisches Nervensystem - Blutgefäß
Figure 2: Sympathetic neuroeffector junction. Norepinephrine (NE) is released from the sympathetic nerve at the sympathetic neuroeffector junction, stimulating postsynaptic alpha1-adrenoreceptors (a1) leading to vasoconstriction. Angiotensin AT1 receptors are present presynaptically at this junction as well as postsynaptically on blood vessels. Stimulation of the presynaptic receptors enhances SNS-induced norepinephrine release. Adapted from Ohlstein [21, 22].

Keywords: AngiotensinAngiotensinblood vesselBlutgefäßGraphische DarstellungJunctionneuroeffectorNeuroeffektorSNSsympathetic nervous systemsympathisches Nervensystem
Angiotensin-II-Antagonisten - Strukturformel
Figure 4: Chemical structures of various angiotensin II antagonists resembling the prototypic compound losartan. Eprosartan exhibits a chemically distinct structure.

Keywords: AngiotensinAngiotensinAntagonistAntagonistChemical structureEprosartanEprosartanLosartanLosartanStrukturformel
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