Different beta-blocking effects of carvedilol and bisoprolol in humans

Koshucharova G et al.

Different beta-blocking effects of carvedilol and bisoprolol in humans

Journal of Clinical and Basic Cardiology 2001; 4 (1): 53-56

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Maximize View	Carvedilol - Bisoprolol - Herzfrequenz Figure 1: Effects of single oral doses of placebo, 25, 50, and 100 mg carvedilol, and 2.5, 5, and 10 mg bisoprolol on heart rate at rest before exercise: 10 mg bisoprolol are significantly more effective than 100 mg carvedilol (p < 0.05). Means +/- SEM; n = 12; *, p < 0.05 (compared to placebo) Keywords: Bisoprolol, Bisoprolol, Carvedilol, Carvedilol, Diagramm, heart rate, Herzfrequenz


Maximize View	Carvedilol - Bisoprolol - Herzfrequenz Figure 2: Effects of single oral doses of placebo, 25, 50, and 100 mg carvedilol, and 2.5 mg, 5 mg, and 10 mg bisoprolol on heart rate at rest after 15 min. of recovery; 10 mg bisoprolol are significantly more effective than 100 mg carvedilol (p < 0.05). Means +/- SEM; n = 12; *, p < 0.05 (compared to placebo) Keywords: Bisoprolol, Bisoprolol, Carvedilol, Carvedilol, Diagramm, heart rate, Herzfrequenz


Maximize View	Carvedilol - Bisoprolol - Herzfrequenz Figure 3: Effects of single oral doses of placebo, 25, 50, and 100 mg carvedilol, and 2.5 mg, 5 mg, and 10 mg bisoprolol on heart rate during exercise: 10 mg bisoprolol appear to be slightly, although not significantly, more effective than 100 mg carvedilol Means +/- SEM; n = 12; *, p < 0.05 (compared to placebo) Keywords: Bisoprolol, Bisoprolol, Carvedilol, Carvedilol, Diagramm, heart rate, Herzfrequenz