Carbohydrate-deficient transferrin in patients with alcoholic cardiomyopathy

Journal of Clinical and Basic Cardiology 1998; 1 (1): 34-36

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Keywords: Alkohol,  Kardiomyopathie,  alcohol,  cardiomyopathy

Carbohydrate-deficient transferrin (CDT) serum concentrations were analysed by a modified radioimmunoassay test in 20 males with alcoholic cardiomyopathy and 30 males with idiopathic dilated cardiomyopathy, and results were compared with reported alcohol intake derived from a structured questionnaire. The test was found to be successful at detecting harmful alcohol intake and alcohol intake above the recommended level. CDT was compared with other known markers of high alcohol intake, and it was found that CDT was a more sensitive and specific marker than g-glutamyltransferase (GT), or mean corpuscular haemoglobin (MCV). These results indicate that CDT is a marker of alcohol intake that can be used to differentiate between alcoholic cardiomyopathy and idiopathic dilated cardiomyopathy in male. J Clin Basic Cardiol 1998; 1: 34-6.