1.
Schlegel U
Central Nervous System Toxicity of Chemotherapy
MRI
European Association of NeuroOncology Magazine 2011; 1 (1): 25-29
(a) MRI (T2-weighted) of the cervicothoracic spine showing extensive
myelopathy (arrows) after intrathecal MTX 12 mg, Ara-C 30 mg + prednisolone 2.5
mg in a 31-year-old male treated for leukaemia (“triple therapy“): tetraplegia
developing over 24 hours shortly after application. (b) Cerebral MRI of the same
patient (FLAIR) showing affection of the pons (arrow) and medulla (arrow) resulting
in coma and mechanic ventilation. Incomplete recovery with persistent paraparesis
and severe bilateral hyakusis.
Keywords:
FLAIR,
MRI