Abbildung 2: Fall-Fracture-Prevention
Threshold for optimal fall and fracture prevention based on double-blind randomized controlled trials. Data points show the relative risk of falls and the relative risk of sustaining any nonvertebral fracture from double-blind RCTs, by achieved 25-hydroxyvitamin D levels in the treatment groups. Data was extracted from two 2009 meta-analyses [8, 9] and summarized in a recent benefit-risk analysis of vitamin D [29]. Based on these data, 75 or better 100 nmol/l (30 or better 40 ng/ml) are suggested as an optimal threshold of 25-hydroxyvitamin D for fall and fracture prevention