Contribution of vitamin D to fracture prevention

Journal für Mineralstoffwechsel & Muskuloskelettale Erkrankungen 2010; 17 (Supplementum 1): 34-38

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Keywords: Mineralstoffwechsel,  Osteoporse,  Vitamin D,  osteoporosis

Several recent meta-analyses have addressed the benefit of vitamin D on fracture reduction with conflicting findings. This article will first summarize anti-fracture efficacy from double-blind randomized trials of oral vitamin D supplementation. Then, this article will address why meta-analyses with alternative approaches, extending to open design trials and trials that tested intra-muscular vitamin D, have reported differential findings.