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Sandmann S, Unger T L- and T-type calcium channel blockade - the efficacy of the calcium channel antagonist mibefradil Journal of Clinical and Basic Cardiology 1999; 2 (2): 187-201 PDF Summary Overview
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Figure/Graphic 8A-B: Kalziumkanal - Mibefradil Cumulative concentration-response curves for the effects of mibefradil, verapamil, and nifedipine on force of contraction in isolated, electrically driven human left ventricular papillary muscle strips. Original records (A) of isometric force of contraction after application of mibefradil (upper) and nifedipine (lower) and a summary of the results (B) are shown. Ordinate in B, force of contraction in percentage of predrug value. Abscissa in B, concentration of drug (in microM). Number of strips is shown in brackets. |
Figure/Graphic 8A-B: Kalziumkanal - Mibefradil
Cumulative concentration-response curves for the effects of mibefradil, verapamil, and nifedipine on force of contraction in isolated, electrically driven human left ventricular papillary muscle strips. Original records (A) of isometric force of contraction after application of mibefradil (upper) and nifedipine (lower) and a summary of the results (B) are shown. Ordinate in B, force of contraction in percentage of predrug value. Abscissa in B, concentration of drug (in microM). Number of strips is shown in brackets. |