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Sandmann S, Unger T L- and T-type calcium channel blockade - the efficacy of the calcium channel antagonist mibefradil Journal of Clinical and Basic Cardiology 1999; 2 (2): 187-201 PDF Summary Overview
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Figure/Graphic 9: Kalziumkanal - Mibefradil Infarct size is given as percentage of left ventricular circumference (%) 6 weeks after induction of myocardial infarction (MI) in rats. Indicated are animals subjected to control MI animals (placebo, black column) and mibefradil-treated animals (10 mg/kg/d p.o.) started at different time points before and after induction of MI (striped columns, 7 d pre, 3 h post, 24 h post, 3 d post, 7 d post). Data represent mean +/- SEM, n = 12-15; * significant versus control MI (p < 0.05). |
Figure/Graphic 9: Kalziumkanal - Mibefradil
Infarct size is given as percentage of left ventricular circumference (%) 6 weeks after induction of myocardial infarction (MI) in rats. Indicated are animals subjected to control MI animals (placebo, black column) and mibefradil-treated animals (10 mg/kg/d p.o.) started at different time points before and after induction of MI (striped columns, 7 d pre, 3 h post, 24 h post, 3 d post, 7 d post). Data represent mean +/- SEM, n = 12-15; * significant versus control MI (p < 0.05). |