MPO Experiments
Figure 1: It shows the results from real-time PCR measurements of all MPO experiments (o2ko: well-oxygenated, no ischaemia, no drug; n2ko: experimental ischaemia, no drug; o2at: well-oxygenated, no ischaemia, atenolol present; n2at: experimental ischaemia, atenolol present; o2neb: well-oxygenated, nebivolol present; n2neb: experimental ischaemia, nebivolol present). Using PCR for validation, we find that during experimental ischaemia, there is an up-regulation of MPO expression. There is a differential regulation between different beta-blockers during myocardial ischaemia, which warrants further investigation.


Keywords: flowchart,  MPO

Interleukin Pathway
Figure 2: Interleukin pathway up-regulated by nebivolol, not by atenolol, during experimental ischaemia.


Keywords: flowchart,  interleukin

CD80 Experiments
Figure 3: It shows the results from real-time PCR measurements of all CD80 experiments (o2ko: well-oxygenated, no ischaemia, no drug; n2ko: experimental ischaemia, no drug; o2at: well-oxygenated, no ischaemia, atenolol present; n2at: experimental ischaemia, atenolol present; o2neb: well-oxygenated, nebivolol present; n2neb: experimental ischaemia, nebivolol present). It can be seen that during experimental ischaemia, there is an up-regulation of CD80 expression. There is also a regulation with and without the influence of beta-blockers during myocardial ischaemia.


Keywords: CD80,  flowchart