Figure/Graphic 2: Dosiswirkungsbeziehung - Cromakalim
Cumulative dose-response curves (DRCs) of cromakalim in the absence (open symbol) and presence of 10 and 50 micromol/L nicorandil (filled symbols), a) in the absence, b) in the presence of 10 micromol/L methylene blue analogous to Figure 1. The symbols and bars represent experimental mean values from 6-12 experiments and 95 % Cl. The following theoretical curves are shown in a) bands of 95 % CI of dose-additive effects of cromakalim in the presence of 10 micromol/L nicorandil, means of independent effects of cromakalim in the presence of 10 and 50 micromol/L nicorandil, b) 95 % CI bands of dose-additive combinations of cromakalim in the presence of 10 and 50 micromol/L nicorandil.