Bals-Pratsch M et al. |
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Genetic Causes in Adrenal or Ovarian Hyperandrogenism in the Reproductive Years Journal für Reproduktionsmedizin und Endokrinologie - Journal of Reproductive Medicine and Endocrinology 2009; 6 (1): 19-23 Volltext (PDF) Summary Praxisrelevanz Abbildungen The most common cause of hyperandrogenism in the reproductive years is PCOS. For several years research has concentrated on identifying potential candidate genes for PCOS without a breakthrough yet. Although PCOS is frequent, rare cases of endocrine neoplasms and late onset CAH have to be distinguished from PCOS. Patients at risk of giving birth to CAH homozygous female fetuses should be offered prenatal dexamethasone treatment to prevent virilization in affected female embryos. |