Weberschock T et al. |
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Das Zikavirus in der andrologischen Beratung // Zika virus in andrologic consultion Journal für Reproduktionsmedizin und Endokrinologie - Journal of Reproductive Medicine and Endocrinology 2018; 15 (1): 6-10 Volltext (PDF) Volltext (HTML) Summary Praxisrelevanz Keywords: Ejakulat, Kinderwunsch, Schwangerschaft, Spermium, Zika Background: Until a few years ago infections with the Zika virus were described as transient and with little symptoms; only recent epidemiogical data could demonstrate their causal relationship to severe neurological disorders. Methods: Supported by a selective PUBMED search a conjoint statement was developed in order to answer the most urgent questions coming up in andrological consulations according to published evidence. Results: Infections with the Zika virus during pregnancy lead to severe neurological defects in approximately 5% with a doubled risk during the first trimester. Infections might also lead rarely to the Guillian-Barré-Syndrome. Infections with the Zika virus are currently reported by more than 80 countries. Transmitted by Aedes mosquitos or by sexual contacts, about 50% of the infections are clinically inapparent. Viral RNA is found in blood and urine only for a short period of time but can persist in semen for up to 6 months. Couples currently planning parenthood are advised not to travel into areas with risk for infection. Otherwise consequent prophylaxis and “safe sex” for 6 months after end of exposurue are recommended. The currentyl available tests for different samples might help stratifying the risk further, but none of them demonstrates hundred percent sensitivity so far. Conclusion: Individual counseling for all couples currently planning parenthood or unprotected sexual intercourse is mandatory.
Kurzfassung: Hintergrund: Bis vor wenigen Jahren waren für die Zikaviruserkrankung nur geringe und zeitlich begrenzte Symptome bekannt; erst die aktuelleren
Daten aus den Epidemien konnten den Zusammenhang mit schwerwiegenden neurologischen Erkrankungen belegen.
Methode: Unterstützt durch eine selektive Literaturrecherche in Pubmed wurde eine gemeinsame Stellungnahme der genannten Fachgesellschaften
erarbeitet, um die drängendsten Fragen in der andrologischen Beratung zu beantworten. |