Buchholz T et al. | ||||
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Polar Body Analysis - Current Clinical Practice and New Developments for Preimplantation Genetic Screening and Diagnosis Journal für Reproduktionsmedizin und Endokrinologie - Journal of Reproductive Medicine and Endocrinology 2009; 6 (1): 32-34 Volltext (PDF) Summary Praxisrelevanz Abbildungen
Keywords: Aneuploidie, Genetisches Screening, Humangenetik, aneuploidy, FISH, PGD, PGS, polar body analysis Polar body analysis is an established procedure identifying oocytes with a high risk of an inherited disorder or with an individual mostly age related chromosomal aneuploidy. New insight into human oocyte meiotic division has come along with controversial discussions about the benefits of the application for screening or diagnostic purpose. New diagnostic methods are requested to prove their value for this very unique material and exclusive approach. |