2.
Köppel H;
Schöllnast R;
Vidalli S
Specific dihydropyridines may affect gating properties of certain subsets of adenosin-triphosphate-dependent K-channels in myocardial tissue and hence modulate its response to ischaemia
Kalium - Ischämie
Journal of Clinical and Basic Cardiology 2000; 3 (2): 133-134
Potassium recordings on the surface of an isolated guinea pig papillary muscle in NT-solution. Ischaemic episodes are indicated with time bars. The preparation is stimulated at a frequency of 1 Hz. Surface recordings show the accumulation of potassium during simulated ischaemia with a subsequent decrease of surface potassium (Ks) upon reperfusion. In the presence of nisoldipine potassium rises to a much lesser extent than in the presence of the drug.
Keywords:
Diagramm,
Ischämie,
Kalium,
Kaliumkanal,
Nisoldipin,
nisoldipine,
potassium,
potassium channel
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