Tamse CT, Lu X, Mortel EG, Cabrales E, Feng W, Schaefer S The Peripheral Benzodiazepine Receptor Modulates Ca2+Transport through the VDAC in Rat Heart Mitochondria Journal of Clinical and Basic Cardiology 2008; 11 (1-4): 24-29 PDF Summary Overview
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Figure/Graphic 4: VDAC-PBR-ANT Representative current traces of VDAC-PBR-ANT channel complex in lipid bilayers. Under control conditions, VDAC-PBR-ANT isolates exhibited characteristic changes in conductance with applied voltages (Section A). Following exposure to hemin 5–10 μM, there was gradual disappearance of conductance changes, resulting in complete channel closure after ~ 3 min (n = 7). The top trace depicts the voltage protocol used for the corresponding current. |
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Figure/Graphic 4: VDAC-PBR-ANT
Representative current traces of VDAC-PBR-ANT channel complex in lipid bilayers. Under control conditions, VDAC-PBR-ANT isolates exhibited characteristic changes in conductance with applied voltages (Section A). Following exposure to hemin 5–10 μM, there was gradual disappearance of conductance changes, resulting in complete channel closure after ~ 3 min (n = 7). The top trace depicts the voltage protocol used for the corresponding current. |