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Gasser R, Roessl U, Holzwart E, Ablasser K, Friehs I, Lewinski D, Pieske B, Mächler H, Trantiner-Yates A, Tscheliessnig KH, Mangge H, Gasser S Shift from Adult to Fetal Metabolic Phenotype During Prolonged Experimental Myocardial Ischemia: A Study on the Effect of Beta Blockers upon Gene Expression of Transmembrane Glucose Transporters Journal of Clinical and Basic Cardiology 2009; 12 (1-4): 11-17 PDF Summary Overview
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Figure/Graphic 2: Real-time PCR Results from real-time PCR measurements of all GLUT4 experiments (o2ko = well-oxygenated, no ischemia, no drug; n2ko = experimental ischemia, no drug; o2at = well-oxygenated, no ischemia, atenolol present; n2at = experimental ischemia, atenolol present; o2neb = well-oxygenated, nebivolol present; n2neb = experimental ischemia, nebivolol present). It can be seen that during experimental ischemia, there is an up-regulation of GLUT4 (SLC2A4) expression, however not statistically significant. |
Figure/Graphic 2: Real-time PCR
Results from real-time PCR measurements of all GLUT4 experiments (o2ko = well-oxygenated, no ischemia, no drug; n2ko = experimental ischemia, no drug; o2at = well-oxygenated, no ischemia, atenolol present; n2at = experimental ischemia, atenolol present; o2neb = well-oxygenated, nebivolol present; n2neb = experimental ischemia, nebivolol present). It can be seen that during experimental ischemia, there is an up-regulation of GLUT4 (SLC2A4) expression, however not statistically significant. |