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Grisold W, Oberndorfer S, Windebank AJ
Chemotherapy and Polyneuropathies
European Association of NeuroOncology Magazine 2012; 2 (1): 25-36

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Fig. 1: CIPN This Image - Fig. 2: Cisplatinum neuropathy Fig. 3: Nerve Roots
Figure/Graphic 2: Cisplatinum neuropathy
Cisplatinum neuropathy. Clinical and electrophysiological features of a 40-year-old male with an ataxic cisplatinum neuropathy. (a) Despite numbness and sensory ataxia no motor involvement with normal small-hand muscles. Nerve conduction velocity (NCV) measurement shows normal motor NCV, (b) the sensory NCV is reduced to 1 uV (pathologic). (c) The feet appear normal, neither atrophy nor trophic changes can be seen. (d) Knee-to-shin is pathologic, vibration perception is absent. (e) Motor NCVs of peroneal nerves are normal. The sural nerve sensory potential is absent; (f) the F wave is normal.
 
Cisplatinum neuropathy
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Figure/Graphic 2: Cisplatinum neuropathy
Cisplatinum neuropathy. Clinical and electrophysiological features of a 40-year-old male with an ataxic cisplatinum neuropathy. (a) Despite numbness and sensory ataxia no motor involvement with normal small-hand muscles. Nerve conduction velocity (NCV) measurement shows normal motor NCV, (b) the sensory NCV is reduced to 1 uV (pathologic). (c) The feet appear normal, neither atrophy nor trophic changes can be seen. (d) Knee-to-shin is pathologic, vibration perception is absent. (e) Motor NCVs of peroneal nerves are normal. The sural nerve sensory potential is absent; (f) the F wave is normal.
 
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