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Grisold W, Oberndorfer S, Windebank AJ Chemotherapy and Polyneuropathies European Association of NeuroOncology Magazine 2012; 2 (1): 25-36 PDF Summary Overview
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Figure/Graphic 3: Nerve Roots Autopsy of the nerve roots, cauda equina and posterior columns of a 74-year-old woman with breast cancer and suspected meningeal carcinomatosis. She received several cycles of intrathecal cytosine arabinoside (Depo-Cyt®). The myelin appears blue with a Klüver staining. (a) Cauda equina. The nerve roots show loss of myelin with a patchy damage to nerve fascicles. (b) Spinal thoracic nerve. Diffuse demyelination. (c) Spinal cord and posterior column: Diffuse loss of myelinated fibres, ballooned degeneration of myelinated fibres. |
Figure/Graphic 3: Nerve Roots
Autopsy of the nerve roots, cauda equina and posterior columns of a 74-year-old woman with breast cancer and suspected meningeal carcinomatosis. She received several cycles of intrathecal cytosine arabinoside (Depo-Cyt®). The myelin appears blue with a Klüver staining. (a) Cauda equina. The nerve roots show loss of myelin with a patchy damage to nerve fascicles. (b) Spinal thoracic nerve. Diffuse demyelination. (c) Spinal cord and posterior column: Diffuse loss of myelinated fibres, ballooned degeneration of myelinated fibres. |