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Koyama K, Hasegawa A
Premature Ovarian Failure Syndrome May Be Induced by Autoimmune Reactions to Zona Pellucida Proteins
Journal für Reproduktionsmedizin und Endokrinologie - Journal of Reproductive Medicine and Endocrinology 2006; 3 (2): 94-97

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Abb. 1a: Zona pellucida Abb. 1b: Zona pellucida Abb. 2: Anti-Zona pellucida antibodies Abb. 3: POF - oocytes Abb. 4: Antibodies - ELISA Aktuelles Bild - Abb. 5: ZP2 peptide
Abbildung 5: ZP2 peptide
Histological examination of ovarian sections from dog immunised with ZP2 peptide. As compared to the control (A), the ovarian section from the immunised dog showed remarkable impairment (B). No growing follicle was detected and a fibrous change was observed in the interstitial tissue.
 
ZP2 peptide
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Abbildung 5: ZP2 peptide
Histological examination of ovarian sections from dog immunised with ZP2 peptide. As compared to the control (A), the ovarian section from the immunised dog showed remarkable impairment (B). No growing follicle was detected and a fibrous change was observed in the interstitial tissue.
 
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