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Gasser R, Klein W Some observations and pathophysiological considerations concerning KATP-channels and coronary heart disease Journal of Clinical and Basic Cardiology 1999; 2 (1): 15-18 PDF Summary Overview
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Figure/Graphic 4: ANP-Freisetzung nach Ischämie Liberation of atrionatriuretic peptide after a short ischaemic episode (PTCA of LAD) in patients with coronary heart disease. The inset shows the concentrations of ANP in the coronary sinus. The curve with open symbols shows the ANP-concentrations of patients from the antecubital vene. The fast rise of ANP leads to peripheral vasodilation, coronary dilatation and elimination of volume by strong diuresis. These mechanisms are cardioprotective by reducing pre- and afterload. |
Figure/Graphic 4: ANP-Freisetzung nach Ischämie
Liberation of atrionatriuretic peptide after a short ischaemic episode (PTCA of LAD) in patients with coronary heart disease. The inset shows the concentrations of ANP in the coronary sinus. The curve with open symbols shows the ANP-concentrations of patients from the antecubital vene. The fast rise of ANP leads to peripheral vasodilation, coronary dilatation and elimination of volume by strong diuresis. These mechanisms are cardioprotective by reducing pre- and afterload. |