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Fitzgerald JS, Poehlmann TG, Suman P, Gupta SK, Schleussner E, Markert  UR
Signal Transducer and Activator of Transcription 3 (STAT3) and Trophoblast Invasion
Journal für Reproduktionsmedizin und Endokrinologie - Journal of Reproductive Medicine and Endocrinology 2007; 4 (6): 322-330

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Abb. 1: Implantation window Aktuelles Bild - Abb. 2: Jak-STAT signal transducing pathway
Abbildung 2: Jak-STAT signal transducing pathway
Jak-STAT signal transducing pathway – 1: cytokine binding to receptor; 2: receptor aggregation; 3: Jaks phosphorylate and activate each other and inner receptor ligand; 4: STATs bind to inner receptor ligand; 5: STATs are activated by Jaks; 6: activated STATs dissociate to form homoand heterodimers; 7: STATs translocate into nucleus; 8: STATs accelerate transcription of target proteins.
 
Jak-STAT signal transducing pathway
Vorheriges Bild Nächstes Bild  


Abbildung 2: Jak-STAT signal transducing pathway
Jak-STAT signal transducing pathway – 1: cytokine binding to receptor; 2: receptor aggregation; 3: Jaks phosphorylate and activate each other and inner receptor ligand; 4: STATs bind to inner receptor ligand; 5: STATs are activated by Jaks; 6: activated STATs dissociate to form homoand heterodimers; 7: STATs translocate into nucleus; 8: STATs accelerate transcription of target proteins.
 
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