Abbildung 15: Telmisartan - Valsartan
Telmisartan 80 mg provides superior blood pressure reductions than valsartan 160 mg following a missed dose. The combined data from two, double-blind, crossover, forced-titration studies are shown.1 Patients with hypertension (n=877) received either telmisartan 80 mg/day or valsartan 160 mg/day. After 4-weeks’ treatment, patients received either double-blind active therapy or placebo (missed dose) for 1 day. After a further 2 weeks’ therapy, patients were crossed over and again received either active therapy or placebo for 1 day. After a missed dose, 24-h mean SBP/DBP was reduced by 10.7/7.2 mmHg with telmisartan, compared with 8.7/5.5 mmHg with valsartan (P<0.05). 1. Lacourcière Y, et al. Sustained antihypertensive activity of telmisartan compared with valsartan. Blood Press Monit 2004; 9: 203–210.