Abbildung 14: Telmisartan - Valsartan
This was a double-blind, forced-titration, crossover, randomized trial that compared telmisartan 80 mg/day with valsartan 160 mg/day in 490 patients with hypertension.1 Ambulatory blood pressure recordings were made at baseline and at 8 weeks. Telmisartan reduced SBP/DBP during the last 6 h of the dosing period by 11/7.6 mmHg, compared with 8.7/5.8 mmHg with valsartan (P=0.02). 1. White WB, et al. Effects of the angiotensin II receptor blockers telmisartan versus valsartan on the circadian variation of blood pressure. Am J Hypertens 2004; 17: 347–353.