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1. Rupp H;
Jäger B;
Verboom C-N
Saving Lives Post-MI: Highly Purified Omega-3 PUFAs for the Prevention of Sudden Death
Omega-3-Fettsäuren - Arrhythmien
Journal of Clinical and Basic Cardiology 2002; 5 (3): 209-214
Highly purified omega-3 PUFAs occupy a unique niche among post-MI medications, being the only therapy to target directly the electrical instability of the myocardium Keywords: Antiarrhythmics,
Antiarrhythmikum,
arrhythmia,
Arrhythmie,
myocardium,
Myokard,
omega-3 fatty acid,
Omega-3-Fettsäure,
PUFA,
PUFA,
Schema
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2. Rupp H;
Jäger B;
Verboom C-N
Saving Lives Post-MI: Highly Purified Omega-3 PUFAs for the Prevention of Sudden Death
GISSI-P-Studie - Plötzlicher Herztod
Journal of Clinical and Basic Cardiology 2002; 5 (3): 209-214
There was evidence for a significant reduction in sudden death with highly purified omega-3 PUFAs in the GISSI-Prevenzione study after 4 months of treatment. Most of the early reduction in total
mortality (p = 0.037 at 3 months) was attributable to the reduction in sudden death; modified from [9] (Calculated adjusting for treatment interaction and major confounding variables) Keywords: Diagramm,
GISSI-P study,
GISSI-P-Studie,
omega-3 fatty acid,
Omega-3-Fettsäure,
plötzlicher Herztod,
PUFA,
PUFA,
sudden death
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3. Rupp H;
Jäger B;
Verboom C-N
Saving Lives Post-MI: Highly Purified Omega-3 PUFAs for the Prevention of Sudden Death
GISSI-P - Risikoreduktion
Journal of Clinical and Basic Cardiology 2002; 5 (3): 209-214
Use of highly purified omega-3 PUFAs in GISSI-Prevenzione was associated with significant reductions in the risk of a primary endpoint event (light bars) and reductions in the risk of several
forms of cause-specific mortality (dark bars). Vitamin E alone had no significant effect on either primary outcome and the combination of highly purified omega-3 PUFAs plus vitamin E was not different from highly purified omega-3 PUFAs alone. Risk reductions derived from 4-way analysis; data from [9] Keywords: Diagramm,
Endpoint,
Endpunkt,
GISSI-P study,
GISSI-P-Studie,
omega-3 fatty acid,
Omega-3-Fettsäure,
PUFA,
PUFA,
reduction,
Reduktion,
Risiko,
risk,
Vitamin E,
Vitamin E
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4. Rupp H;
Jäger B;
Verboom C-N
Saving Lives Post-MI: Highly Purified Omega-3 PUFAs for the Prevention of Sudden Death
GISSI-P - Endpunkte
Journal of Clinical and Basic Cardiology 2002; 5 (3): 209-214
Nested endpoints classification used in GISSI-Prevenzione. All endpoints were confirmed by a blinded Endpoint Validation Committee. CVD = cardiovascular (CV) death (any CV cause); CD = cardiac death (any cardiac cause); CHD = coronary death (any coronary cause); data from [8] Keywords: Endpoint,
Endpunkt,
GISSI-P study,
GISSI-P-Studie,
Schema
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5. Rupp H;
Jäger B
The renin-angiotensin system and the sympathetic nervous system in hypertension and congestive heart failure: implications for therapeutic interventions
Angiotensin-II-Antagonisten - Strukturformel
Journal of Clinical and Basic Cardiology 2001; 4 (1): 47-51
Chemical structures of various angiotensin II antagonists resembling the prototypic compound losartan. Eprosartan exhibits a chemically distinct structure. Keywords: Angiotensin,
Angiotensin,
Antagonist,
Antagonist,
Chemical structure,
Eprosartan,
Eprosartan,
Losartan,
Losartan,
Strukturformel
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6. Rupp H;
Jäger B
The renin-angiotensin system and the sympathetic nervous system in hypertension and congestive heart failure: implications for therapeutic interventions
Sympathisches Nervensystem - Blutgefäß
Journal of Clinical and Basic Cardiology 2001; 4 (1): 47-51
Sympathetic neuroeffector junction. Norepinephrine (NE) is released from the sympathetic nerve at the sympathetic neuroeffector junction, stimulating postsynaptic alpha1-adrenoreceptors (a1) leading to vasoconstriction. Angiotensin AT1 receptors are present presynaptically at this junction as well as postsynaptically on blood vessels. Stimulation of the presynaptic receptors enhances SNS-induced norepinephrine release. Adapted from Ohlstein [21, 22]. Keywords: Angiotensin,
Angiotensin,
blood vessel,
Blutgefäß,
Graphische Darstellung,
Junction,
neuroeffector,
Neuroeffektor,
SNS,
sympathetic nervous system,
sympathisches Nervensystem
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7. Rupp H;
Jäger B
The renin-angiotensin system and the sympathetic nervous system in hypertension and congestive heart failure: implications for therapeutic interventions
RAS und SNS
Journal of Clinical and Basic Cardiology 2001; 4 (1): 47-51
The relationship between the renin-angiotensin system and the sympathetic nervous system (SNS) Keywords: RAS,
RAS,
renin-angiotensin system,
Renin-Angiotensin-System,
Schema,
SNS,
SNS,
sympathetic nervous system,
Sympathikus,
sympathisches Nervensystem
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