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Uckermann O, Galli R, Mackenroth L, Geiger K, Steiner G, Koch E, Schackert G, Kirsch M
Optical Biochemical Imaging: Potential New Applications in Neuro-Oncology
European Association of NeuroOncology Magazine 2014; 4 (1): 20-26

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Fig. 1: Vibrational Spectroscopy Fig. 2A-D: FT-IR imaging Fig. 3: CARS image Fig. 4a-f: Multimodal NLO This Image - Fig. 5a-c: NLO imaging
Figure/Graphic 5a-c: NLO imaging
Multimodal NLO imaging of human tumours (red: CARS, green: TPEF, blue: SHG), overlaid with the bright field images of the unstained sample. The technique allows to retrieve detailed morphochemical information about tissue structure and properties on unstained samples. (a) Cryosection of human glioblastoma (scale bar: 200 μm). (b) High magnification of the border between tumour and normal tissue as indicated in (a). (c) Cryosection of human neuroma (scale bar: 0.5 mm).
 
NLO imaging
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Figure/Graphic 5a-c: NLO imaging
Multimodal NLO imaging of human tumours (red: CARS, green: TPEF, blue: SHG), overlaid with the bright field images of the unstained sample. The technique allows to retrieve detailed morphochemical information about tissue structure and properties on unstained samples. (a) Cryosection of human glioblastoma (scale bar: 200 μm). (b) High magnification of the border between tumour and normal tissue as indicated in (a). (c) Cryosection of human neuroma (scale bar: 0.5 mm).
 
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